Throughout history all forms of life on Earth have experienced many changes. But two things have remained constant. All life has evolved in 1g gravity and within and as a part of the natural world. This connection has been encoded in our genes over millions of years. We are inextricably entwined with nature in ways that we don’t fully understand. Our nervous systems, sensory expectations, emotional responses have emerged from this relationship. This webcast will explore the various aspects around this connection and challenge in extended space missions, including Project Babylon a new initiative surrounding what humanity must carry beyond Earth in order not only to survive but to remain psychologically, biologically socially, and creatively human.